|
| |
Crielaard Wim, ACTA Amsterdam, The Netherlands | 
| 
| 
| 
Terug
|
Exploring the microbial diversity in oral biofilms using an oral cavity ecology chip |
|
B.J.F. Keijser (1) E. Zaura (2), S.M. Huse (3), J.M.B.M. van der Vossen (1), F.H.J. Schuren (1), R.C. Montijn (1), J.M. ten Cate (2), W. Crielaard (2)
|
|
(1) TNO-Quality of Life, Zeist, Netherlands
(2) Academic Centre for Dentistry Amsterdam, Amsterdam, Netherlands, w.crielaard@acta.nl
(3) Josephine Bay Paul Center, Marine Biological Laboratory, MA, United States of America |
|
|
|
|
|
The oral cavity is a complex microbial niche, housing a large diversity of microorganisms. It has been known for quite some time the composition and activity of the oral microbial flora is intimately related to oral health status. To explore the oral microbial flora in relation to oral health in more detail, we have developed the oral cavity chip (OC chip). The OC chip enables the simultaneous monitoring of 400 of the most relevant oral microorganisms. The detection limit of the chip lies in the order of 10^3 bacteria per ml. We have used the chip, to monitor the spatial distribution and temporal changes in the oral microbial flora. Clear distinction could be made in the soft tissue niches and lingual en buccal site of the hard tissues. The development of the OC chip can provides a significant contribution in the understanding between the oral microbial flora and oral health. |
|
|
|
|
|
|
| |
| |
