The main cause of halitosis is the bacterial decomposition of organic material. This releases volatile sulphur compounds (VSC), which are primarily responsible for bad breath. Thus patients with halitosis often have raised organoleptic values. These are measured in a process whereby a trained investigator assesses the oral malodour using his sense of smell. Halitosis can entail considerable restrictions in the social life of those patients who are affected.
Using meridol HALITOSIS mouthrinse twice daily results in a clear reduction of oral malodour in patients with raised organoleptic and VSC values. This was the finding of a scientific study conducted by Dr. Walter Wigger-Alberti with his team at the proDERM Institute of Applied Dermatological Research. The three-week randomised, stratified and double-blind clinical trial tested the efficacy of meridol HALITOSIS mouthrinse in subjects who were affected by oral malodour. A total of 174 subjects took part in this study, divided into one test group and three control groups of equal size. The test subjects had both a raised organoleptic baseline value and also an increased concentration of hydrogen sulphide in the breath. The participants were stratified according to their organoleptic baseline value. All the groups brushed their teeth twice daily with a meridol toothbrush and a standard toothpaste, which had a fluoride content of 1400 ppm. In the course of the study the test group additionally rinsed their mouths in the morning and in the evening with meridol HALITOSIS mouthrinse. The benchmark control group used an antiseptic mouthrinse, the positive control group a CHX mouthrinse and the negative control group used water to rinse. Data was collected after the first, seventh and 21st day.
Subjects who used meridol HALITOSIS mouthrinse showed a significant reduction in organoleptic values overnight after only the first application. This positive effect remained constant in the course of the study, as the data collected after the 7th and 21st day demonstrated. The confidence interval was 95 %. In comparison to the negative control group, the VSC levels in patients using the meridol HALITOSIS mouthrinse were reduced by more than 50 % after the first day of application. This outstanding result was also repeated in the subsequent data collections. Here the confidence interval was likewise 95 %.
“The good results of meridol HALITOSIS mouthrinse are due to the active ingredients amine fluoride, stannous fluoride and zinc lactate. This active ingredient combination actively combats odour-causing bacteria and volatile sulphur compounds, which are regarded as the main cause of the development of oral malodour”, explains Baerbel Kiene, Director Scientific Affairs at GABA International. “In addition, the fluoride contained in meridol HALITOSIS mouthrinse offers effective protection against caries. This means that patients can effectively fight oral malodour with the latest product from meridol Research, without neglecting other aspects of complete oral care.”
Literature: Wigger-Alberti W, Gysen K, Axmann EM, Wilhelm KP. Europerio 6, June 4-6 2009, Stockholm, Sweden
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